Is Losing Hair a Typical Side Effect of Trifexis?


    Here is a Question from Christy asking if Losing Hair could be a Side Effect of Trifexis.

    “A few months ago I started giving my 2 year old BT Trifexis and since he has started to lose his hair. He has a bald spot now on one hip.

    Is this a typical side effect of Trifexis or is this just a strange coincidence?? (Bald spot not shown on the following picture.)”

    Is losing hair a typical side effect of Trifexis

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    HughGeriBeckyRaySherry Phelps Recent comment authors
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    Get a skin scrape at your vet for Dermetex mites. I found out my Brit had it handed down from the mother. Bald spot forming between the nose and on the elbows. got the meds for 2 weeks and went away.


    The boston terrier rescue here in Fl told me not to use trifexis on my dog ,, instead to use bravecta and heart guard. Bostons dont do to well on trifexis.


    My 2 yr old American Bully has been on Trifexis but thinking of taking him off he has had dry flaky skin and losing small patches of hair on back and sides of stomach. He never had this issue before


    My 6yo Chihuahua is having the exact same response. There is no redness just big flaky spots and the hair comes right out.

    Sherry Phelps

    Mine lost hair from allergies (grass and pollen). We go through this every year Feb through November. Any excessive itching? Get you baby to the vet either way…please

    Christy Shahal Harris

    I haven’t had any trouble from it and I have 3 of my babies on it.

    Joanne Rose-Foster

    Best bet to go see your vet! That’s my opinion! 🙂

    Shawn Reaser

    Hair loss and itching are some of the side effects. My bostie cannot tolerate other meds at all so Trifexis is the best for right now for her. You maytry some hydrocortizone spray on the area to see if it’s a topical allergy issue.Advantage and Frontline tend to be bad for bosties from my experience. I’d talk to your vet about it and see if there is something else.

    Christy Mitchell

    I had him on Advantage II but that made him lethargic. The hair loss started around the same time I switched him to Trifexis but it could be caused by something else entirely.


    My boston takes it he’s fine but its just like I can take a medicine that may give another person a side affect but I’m fine so every dog is different too I’d call the vet especially cause he’s losing hair. Boston’s are prone to skin conditions and allergies my dog gets bumps and loses hair if he eats food or treats that have a lot of fillers if it is allergies try blue buffalo it’s a more natural food and try have a lot of options and flavors with no fillers and try make treats at the pet store… Read more »

    Dawn Russell

    I’ve never experienced this with Trifexis. Only with the ones that you put on their skin like Advantage.

    Robin Cook

    I give my boston trifexis and she’s fine.